RAS PresidiumДоклады Российской академии наук. Науки о жизни Doklady Biological Sciences

  • ISSN (Print) 2686-7389
  • ISSN (Online) 3034-5057

EFFECT OF A COMPARATIVE ANALYSIS OF DIFFERENT ANNOTATIONS OF THE ORYZA SATIVA RICE GENOME FOR IN SILICO VERIFICATION OF PREDICTED PROMOTER SEQUENCES

PII
S30345057S2686738925040124-1
DOI
10.7868/S3034505725040124
Publication type
Article
Status
Published
Authors
Volume/ Edition
Volume 523 / Issue number 1
Pages
452-456
Abstract
In this study, promoter sequences predicted by the MAHDS method in the Oryza sativa genome were analyzed using three genome annotations: RefSeq NCBI, Rice Genome Annotation Project, and Ensembl. A portion of the predicted promoters was found to be located near annotated genes, indicating their potential functional role. The remaining sequences, considered as potentially novel regulatory elements, were examined using YAPP for the presence of core promoter motifs and their functional combinations. All analyzed predicted promoters contain either an Inr or a TATA motif – key elements involved in transcription initiation. The identified motif combinations suggest a high likelihood of transcriptional activity in these sequences, while the consistency of the results with annotated data and CAGE-seq signals supports the reliability and applicability of the MAHDS method.
Keywords
предсказанные промоторные последовательности MAHDS метод Oryza sativa мотивы корового промотора аннотации генома транскрипты
Date of publication
15.06.2025
Year of publication
2025
Number of purchasers
0
Views
33

References

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